Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.85 |
| ▸ | KDR | P35968 | 16/20 | 0.72 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12376541 | 0.92 | MET (1.00) | METKDRKITPDGFRA | |
| SCHEMBL3564743 | 0.90 | MET (0.75) | METKDRKITPDGFRA | |
| SCHEMBL3572865 | 0.89 | MET (0.72) | METKDRKITPDGFRA | |
| SCHEMBL3561459 | 0.89 | MET (0.74) | METKDRKITPDGFRA | |
| SCHEMBL3563117 | 0.86 | MET (1.00) | METKDRKITPDGFRA | |
| SCHEMBL2282742 | 0.84 | MET (1.00) | METKDR | |
| SCHEMBL1878803 | 0.82 | MET (0.77) | METKDRKITPDGFRA | |
| SCHEMBL4321802 | 0.79 | MET (0.54) | METKDRKITPDGFRA | |
| SCHEMBL3623301 | 0.79 | MET (0.72) | METKDR | |
| SCHEMBL12376537 | 0.79 | MET (1.00) | METKDRKITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121125-A1 | ETHER-LINKED HETEROARYL COMPOUNDS | PFIZER INC. (US) | 2005-12-22 | — | — | WO | disclosed |