Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7374974 | 0.89 | TSHR (0.43) | TSHREPHX1BIRC2NPC1RAB9A | |
| SCHEMBL31440730 | 0.87 | EPHX1 (0.46) | EPHX1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7771457 | 0.87 | EPHX1 (0.46) | EPHX1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL27495595 | 0.87 | SMN1; SMN2 (0.48) | TSHREPHX1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7368739 | 0.86 | EPHX1 (0.44) | EPHX1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL476725 | 0.85 | EPHX1 (0.47) | EPHX1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL459574 | 0.85 | EPHX1 (0.47) | EPHX1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL459573 | 0.85 | EPHX1 (0.47) | EPHX1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL8215965 | 0.84 | ALDH1A1 (0.50) | EPHX1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL11638915 | 0.84 | EPHX1 (0.46) | EPHX1NPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100497323-C | New heterocyclic oxime compounds, preparing process and medical composition thereof | SERVIER LAB (FR) | 2009-06-10 | — | — | CN | disclosed |
| CN-1590379-A | New heterocyclic oxime compounds, preparing process and medical composition thereof | SERVIER LAB (FR) | 2005-03-09 | — | — | CN | disclosed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |