Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 9/20 | 0.70 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.70 |
| ▸ | ACACB | O00763 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152894 | 1.00 | ADRB1 (0.70) | ADRB1ADRB3ACACBPPARGADRB2 | |
| SCHEMBL7152889 | 1.00 | ADRB1 (0.70) | ADRB1ADRB3ACACBPPARGADRB2 | |
| SCHEMBL7151700 | 0.90 | ADRB3 (0.73) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7151697 | 0.90 | ADRB3 (0.73) | ADRB1ADRB3ADRB2 | |
| SCHEMBL7146436 | 0.86 | ADRB3 (0.67) | ADRB1ADRB3ADRB2CASP3CASP6 | |
| SCHEMBL7146434 | 0.86 | ADRB3 (0.67) | ADRB1ADRB3ADRB2CASP3CASP6 | |
| SCHEMBL9006683 | 0.85 | ADRB1 (0.95) | ADRB1ADRB3ADRB2CASP3CASP6 | |
| SCHEMBL7143110 | 0.85 | ADRB1 (0.95) | ADRB1ADRB3ADRB2CASP3CASP6 | |
| SCHEMBL7143114 | 0.85 | ADRB1 (0.95) | ADRB1ADRB3ADRB2CASP3CASP6 | |
| SCHEMBL7148911 | 0.84 | ADRB3 (0.72) | ADRB1ADRB3ADRB2CASP3CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | claimed |
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |