Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529595 | 0.81 | PPARG (0.48) | PPARGTSHRMAPTFFAR1ALDH1A1 | |
| SCHEMBL6506714 | 0.77 | PPARG (0.48) | PPARGTSHRMAPTFFAR1ALDH1A1 | |
| SCHEMBL6505839 | 0.76 | PPARG (0.46) | PPARGTSHRMAPTFFAR1ALDH1A1 | |
| SCHEMBL6512061 | 0.76 | PIM1 (0.45) | PTAFRTSHRALDH1A1NPSR1HPGD | |
| SCHEMBL6512065 | 0.76 | PIM1 (0.45) | PTAFRTSHRALDH1A1NPSR1HPGD | |
| SCHEMBL6509096 | 0.76 | PPARG (0.50) | PPARGMAPTFFAR1PPARAHRH3 | |
| SCHEMBL6528104 | 0.74 | PPARG (0.43) | PPARGTSHRMAPTFFAR1ALDH1A1 | |
| SCHEMBL6508034 | 0.73 | FFAR1 (0.68) | PPARGMAPTFFAR1PPARA | |
| SCHEMBL8128813 | 0.70 | PPARG (0.63) | PPARGTSHRMAPTFFAR1ALDH1A1 | |
| SCHEMBL6506192 | 0.69 | MAPT (0.51) | PPARGTSHRMAPTFFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | claimed |
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |