Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | FPR2 | P25090 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121082 | 0.84 | FFAR1 (0.55) | PPARGHDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL6514244 | 0.79 | PIM1 (0.49) | HDAC6FPR2LMNAMAPTUSP2 | |
| SCHEMBL6533562 | 0.79 | PIM1 (0.49) | HDAC6FPR2LMNAMAPTUSP2 | |
| SCHEMBL6505379 | 0.78 | FPR2 (0.49) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6529595 | 0.77 | PPARG (0.48) | PPARGFFAR1MAPTCYP3A4TP53 | |
| SCHEMBL6506248 | 0.77 | PTAFR (0.44) | PPARGFFAR1MAPTCYP3A4TP53 | |
| SCHEMBL8128813 | 0.72 | PPARG (0.63) | PPARGFFAR1MAPTCYP3A4TP53 | |
| SCHEMBL6505839 | 0.69 | PPARG (0.46) | PPARGFFAR1MAPTCYP3A4TP53 | |
| SCHEMBL6509096 | 0.69 | PPARG (0.50) | PPARGFFAR1MAPTHRH3 | |
| SCHEMBL6528104 | 0.67 | PPARG (0.43) | PPARGFFAR1MAPTCYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | claimed |
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |