Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PIM1 | P11309 | 4/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506413 | 1.00 | PPARG (0.47) | PPARGPIM1PIM2PIM3GSK3B | |
| SCHEMBL12520463 | 0.81 | PPARG (0.68) | PPARGPIM1PIM2HPGD | |
| SCHEMBL1848738 | 0.81 | PPARG (0.68) | PPARGPIM1PIM2HPGD | |
| SCHEMBL1848740 | 0.81 | PPARG (0.68) | PPARGPIM1PIM2HPGD | |
| SCHEMBL6514148 | 0.81 | PPARG (0.68) | PPARGPIM1PIM2PIM3GSK3B | |
| SCHEMBL1848112 | 0.80 | PPARG (0.61) | PPARGPIM1PIM2HPGD | |
| SCHEMBL1848111 | 0.80 | PPARG (0.61) | PPARGPIM1PIM2HPGD | |
| SCHEMBL12521873 | 0.80 | PPARG (0.61) | PPARGPIM1PIM2HPGD | |
| SCHEMBL12521883 | 0.79 | PPARG (0.61) | PPARGPIM1PIM2HPGD | |
| SCHEMBL1851183 | 0.79 | PPARG (0.61) | PPARGPIM1PIM2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |