Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.44 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.43 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6530823 | 0.85 | PPARG (0.59) | PPARGHDAC4HDAC8PIM1PIM2 | |
| SCHEMBL2177329 | 0.81 | PPARG (1.00) | PPARGHDAC4HDAC8PTPN11PIM1 | |
| SCHEMBL6506410 | 0.81 | PPARG (0.47) | PPARGPIM1PIM2PIM3GSK3B | |
| SCHEMBL6506413 | 0.81 | PPARG (0.47) | PPARGPIM1PIM2PIM3GSK3B | |
| SCHEMBL2177332 | 0.81 | PPARG (1.00) | PPARGHDAC4HDAC8PTPN11PIM1 | |
| SCHEMBL12520491 | 0.81 | PPARG (1.00) | PPARGHDAC4HDAC8PTPN11PIM1 | |
| SCHEMBL12521900 | 0.80 | PPARG (0.91) | PPARGHDAC4HDAC8PTPN11PIM1 | |
| SCHEMBL6511223 | 0.76 | PPARG (0.70) | PPARG | |
| SCHEMBL12521729 | 0.74 | PPARG (1.00) | PPARGHDAC4HDAC8PTPN11PIM1 | |
| SCHEMBL12521723 | 0.73 | PPARG (0.78) | PPARGHDAC4HDAC8PTPN11PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | claimed |
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |