Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | PPARD | Q03181 | 3/20 | 0.63 |
| ▸ | PPARA | Q07869 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3062492 | 0.87 | MTNR1A (0.60) | HDAC1HTTHPGDPPARDPPARA | |
| SCHEMBL6848785 | 0.86 | HTT (0.83) | HDAC1HTTHPGDALDH1A1GAA | |
| SCHEMBL13947285 | 0.85 | HDAC1 (0.79) | HDAC1HTTHPGDALDH1A1GAA | |
| SCHEMBL6570631 | 0.85 | HDAC1 (1.00) | HDAC1HTTHPGDALDH1A1GAA | |
| SCHEMBL27610689 | 0.85 | HDAC1 (0.79) | HDAC1HTTHPGDALDH1A1GAA | |
| SCHEMBL14082594 | 0.84 | HTT (0.61) | HDAC1HTTHPGDPPARDPPARA | |
| SCHEMBL94368 | 0.83 | HDAC1 (0.77) | HDAC1HTTHPGDALDH1A1GAA | |
| SCHEMBL12218093 | 0.83 | HDAC1 (0.82) | HDAC1HTTHPGDALDH1A1GAA | |
| SCHEMBL12218248 | 0.83 | HDAC1 (0.77) | HDAC1HTTHPGDALDH1A1GAA | |
| SCHEMBL1568381 | 0.83 | HDAC1 (0.72) | HDAC1HTTHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |