Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 5/20 | 0.35 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21639196 | 0.88 | NPSR1 (0.45) | NPSR1ALDH1A1RAB9AHSD17B10KDM4E | |
| SCHEMBL539769 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2BMP1 | |
| SCHEMBL28883148 | 0.79 | NPSR1 (0.40) | NPSR1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL23214145 | 0.78 | NPSR1 (0.50) | NPSR1ALDH1A1RAB9AHSD17B10KDM4E | |
| SCHEMBL13247707 | 0.77 | NPSR1 (0.54) | NPSR1ALDH1A1RAB9AHSD17B10KDM4E | |
| SCHEMBL20530816 | 0.74 | FBP1 (0.59) | NPSR1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL21639351 | 0.74 | ATM (0.45) | ALDH1A1RAB9AHSD17B10KDM4EHPGD | |
| SCHEMBL21639431 | 0.73 | NPSR1 (0.48) | NPSR1ALDH1A1RAB9AHSD17B10KDM4E | |
| SCHEMBL28352773 | 0.72 | NPSR1 (0.44) | NPSR1ALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL2845053 | 0.71 | NPSR1 (0.47) | NPSR1ALDH1A1RAB9AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |