SCHEMBL6506525

SCHEMBL6506525

CCCC=COCc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.43
AGXT P21549 1/20 0.42
TSHR P16473 2/20 0.41
TP53 P04637 1/20 0.38
ALDH1A1 P00352 2/20 0.37
HCAR2 Q8TDS4 1/20 0.37
MAOB P27338 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.36
MAPK1 P28482 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MAPT P10636 1/20 0.36
CETP P11597 3/20 0.36
BCHE P06276 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1068376 0.89 IDO1 (0.41) IDO1AGXTTSHRALDH1A1L3MBTL1
SCHEMBL1068374 0.89 IDO1 (0.41) IDO1AGXTTSHRALDH1A1L3MBTL1
SCHEMBL8650650 0.86 EPHX2 (0.47) CETP
SCHEMBL8650647 0.86 EPHX2 (0.47) CETP
SCHEMBL22207390 0.86 EPHX2 (0.47) CETP
SCHEMBL7717208 0.84 IDO1 (0.46) IDO1AGXTTSHRTP53ALDH1A1
SCHEMBL7717207 0.84 IDO1 (0.46) IDO1AGXTTSHRTP53ALDH1A1
SCHEMBL30712620 0.81 HCAR2 (0.40) IDO1TP53HCAR2
SCHEMBL2878220 0.81 IDO1 (0.35) IDO1AGXTCYP3A4
SCHEMBL29447243 0.81 IDO1 (0.43) IDO1AGXTTSHRALDH1A1HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005103015-A1 TRIAZINE COMPOUNDS AND THEIR ANALOGS, COMPOSITIONS, AND METHODS REDDY US THERAPEUTICS, INC. (US) 2005-11-03 WO disclosed
WO-2005062811-A2 CATALYTIC SULFOXIDE-PROMOTED C-H OXIDATION, AND REGIOSELECTIVE PREPARATION OF ALLYLIC CARBOXYLATES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2005-07-14 WO disclosed