Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | AGXT | P21549 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717208 | 1.00 | IDO1 (0.46) | IDO1AGXTTSHRTP53ALDH1A1 | |
| SCHEMBL6506525 | 0.84 | IDO1 (0.43) | IDO1AGXTTSHRTP53ALDH1A1 | |
| SCHEMBL27509183 | 0.82 | TSHR (0.57) | IDO1AGXTTSHRALDH1A1MAOB | |
| SCHEMBL1068376 | 0.81 | IDO1 (0.41) | IDO1AGXTTSHRALDH1A1MAPK1 | |
| SCHEMBL1068374 | 0.81 | IDO1 (0.41) | IDO1AGXTTSHRALDH1A1MAPK1 | |
| SCHEMBL17269304 | 0.81 | MAOB (0.58) | IDO1AGXTTSHRALDH1A1MAOB | |
| SCHEMBL20750998 | 0.80 | TSHR (0.38) | IDO1AGXTTSHRALDH1A1MAOB | |
| SCHEMBL23553983 | 0.79 | IDO1 (0.36) | IDO1AGXTTSHRTP53ALDH1A1 | |
| SCHEMBL738243 | 0.79 | IDO1 (0.46) | IDO1AGXTTSHRALDH1A1MAOB | |
| SCHEMBL1257815 | 0.79 | IDO1 (0.46) | IDO1AGXTTSHRALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10195189-B2 | 2-phenethenyltetrahydro isoquinolines useful as anti-HIV compounds | Prosetta Antiviral, Inc. (US) | 2019-02-05 | — | — | US | disclosed |
| WO-2017132463-A1 | SURFACE PRIMER COMPOSITIONS AND METHODS OF USE | ACatechol, Inc. (US) | 2017-08-03 | — | — | WO | disclosed |
| US-20020037534-A1 | Combinatorial preparation of a substance library with removal of a zwitterionic compound by precipitation | BASF AKTIENGESELLSCHAFT (DE) | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037534-A1 | Combinatorial preparation of a substance library with removal of a zwitterionic compound by precipitation | NEFM, PSPH, NGLY1 | IDO1 3207/4885AGXT 2815/4885TSHR 3420/4885 |
| US-10195189-B2 | 2-phenethenyltetrahydro isoquinolines useful as anti-HIV compounds | MAVS, EIF2AK2, POLRMT | IDO1 135/4885AGXT 4118/4885TSHR 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.