Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5354696 | 0.92 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL1712999 | 0.92 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL13449147 | 0.82 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL1712917 | 0.82 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL1712888 | 0.79 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL6184735 | 0.75 | BDKRB1 (0.84) | BDKRB1 | |
| SCHEMBL10147800 | 0.74 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL4036439 | 0.74 | BDKRB1 (0.81) | BDKRB1 | |
| SCHEMBL10182378 | 0.73 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL1713001 | 0.72 | BDKRB1 (0.68) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288305-A1 | N-biarylmethyl aminocycloalkanecarboxamide derivatives | MERCK SHARP & DOHME CORP. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288305-A1 | N-biarylmethyl aminocycloalkanecarboxamide derivatives | BDKRB1, BDKRB2, LTB4R2 | BDKRB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.