Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3685973 | 0.84 | ALDH1A1 (0.50) | HPGDSMN1; SMN2L3MBTL1ALDH1A1CNR1 | |
| SCHEMBL7512969 | 0.76 | SMYD3 (0.43) | SMN1; SMN2L3MBTL1ALDH1A1CNR1NPC1 | |
| SCHEMBL4000977 | 0.73 | GRM5 (0.62) | SMN1; SMN2MAPTALDH1A1KDM4EGAA | |
| SCHEMBL3679576 | 0.73 | MAPT (0.68) | HPGDSMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL17396100 | 0.72 | PBK (0.52) | — | |
| SCHEMBL20497247 | 0.72 | PBK (0.52) | — | |
| SCHEMBL965456 | 0.72 | NPSR1 (0.30) | — | |
| SCHEMBL9212654 | 0.70 | HRH4 (0.48) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL13485764 | 0.69 | — | — | |
| SCHEMBL22372167 | 0.69 | CNR1 (0.45) | HDAC6ALDH1A1KDM4ECNR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009974-A1 | IMIDAZOLE COMPOUNDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-02-03 | — | — | WO | disclosed |