Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510545 | 0.82 | SMPD1 (0.34) | — | |
| SCHEMBL7169209 | 0.79 | SMPD1 (0.36) | — | |
| SCHEMBL7210763 | 0.74 | SMPD1 (0.39) | S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL7210769 | 0.73 | SMPD1 (0.32) | — | |
| SCHEMBL7055514 | 0.73 | — | — | |
| SCHEMBL6531141 | 0.73 | — | — | |
| SCHEMBL6503879 | 0.72 | SMPD1 (0.40) | — | |
| SCHEMBL6699834 | 0.72 | SMPD1 (0.36) | — | |
| SCHEMBL5362490 | 0.72 | S1PR2 (0.38) | S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL7057585 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047236-A1 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-05-26 | — | — | WO | disclosed |