Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169209 | 0.92 | SMPD1 (0.36) | SMPD1 | |
| SCHEMBL7210763 | 0.86 | SMPD1 (0.39) | SMPD1 | |
| SCHEMBL6699834 | 0.85 | SMPD1 (0.36) | SMPD1 | |
| SCHEMBL6510545 | 0.85 | SMPD1 (0.34) | SMPD1 | |
| SCHEMBL6503075 | 0.82 | SMPD1 (0.30) | SMPD1 | |
| SCHEMBL6503879 | 0.82 | SMPD1 (0.40) | SMPD1 | |
| SCHEMBL6504573 | 0.81 | SMPD1 (0.42) | SMPD1 | |
| SCHEMBL6708693 | 0.80 | SMPD1 (0.30) | SMPD1 | |
| SCHEMBL6898367 | 0.77 | SMPD1 (0.30) | SMPD1 | |
| SCHEMBL6531141 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1366024-A2 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2003-12-03 | — | — | EP | disclosed |
| WO-2002030882-A2 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |