Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TPO | P07202 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23926996 | 0.86 | KDM4E (0.78) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL1498279 | 0.86 | KDM4E (0.65) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL30079741 | 0.86 | KDM4E (0.78) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6306219 | 0.86 | KDM4E (1.00) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL4059342 | 0.81 | KDM4E (0.69) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL2974010 | 0.80 | HAO1 (0.51) | KDM4EPOLBMEN1KMT2AHAO1 | |
| SCHEMBL8736734 | 0.80 | KDM4E (0.57) | KDM4EPOLBMEN1KMT2ARAB9A | |
| SCHEMBL20931746 | 0.80 | KDM4E (0.79) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5342115 | 0.79 | KDM4E (0.62) | KDM4EPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6506490 | 0.79 | KDM4E (0.68) | KDM4EPOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005037839-A1 | NORCANTHARIDIN DERIVATIVE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, COMPOSITIONS CONTAINING SAID COMPOUNDS AND THE USE THEREOF | ENTOMED (FR) | 2005-04-28 | — | — | WO | disclosed |
| EP-0072529-B1 | SULFUR-SUBSTITUTED PHENOXYPYRIDINES HAVING ANTIVIRAL ACTIVITY | THE DOW CHEMICAL COMPANY (US) | 1986-01-29 | — | — | EP | disclosed |
| EP-0072529-A1 | Sulfur-substituted phenoxypyridines having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1983-02-23 | — | — | EP | disclosed |
| US-4371537-A | Sulfur-substituted phenoxypyridines having antiviral activity | THE DOW CHEMICAL COMPANY (US) | 1983-02-01 | — | — | US | disclosed |