Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2269214 | 0.68 | MET (0.63) | MET | |
| SCHEMBL5228252 | 0.66 | MET (1.00) | MET | |
| SCHEMBL5888084 | 0.65 | MET (0.69) | MET | |
| SCHEMBL5888437 | 0.65 | MET (0.77) | MET | |
| SCHEMBL5888513 | 0.64 | MET (0.85) | MET | |
| SCHEMBL5888485 | 0.62 | MET (0.72) | MET | |
| SCHEMBL5888549 | 0.62 | MET (0.66) | MET | |
| SCHEMBL12127087 | 0.62 | HTR2A (0.33) | — | |
| SCHEMBL5888321 | 0.61 | MET (1.00) | MET | |
| SCHEMBL5888590 | 0.61 | MET (0.59) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005004808-A2 | TETRACYCLIC COMPOUNDS AS c-MET INHIBITORS | SUGEN, INC. (US) | 2005-01-20 | — | — | WO | disclosed |