Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.50 |
| ▸ | PPARG | P37231 | 11/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897418 | 0.88 | PPARA (0.47) | PPARAPPARGPPARDPOLBLMNA | |
| SCHEMBL4904501 | 0.86 | PPARA (0.47) | PPARAPPARGPPARDPOLBLMNA | |
| SCHEMBL4894405 | 0.82 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL4904561 | 0.81 | PPARA (0.56) | PPARAPPARGPPARDPOLBLMNA | |
| SCHEMBL4903588 | 0.80 | LMNA (0.53) | PPARAPPARGPPARDPOLBLMNA | |
| SCHEMBL4904113 | 0.77 | LMNA (0.51) | PPARAPPARGPPARDPOLBLMNA | |
| SCHEMBL6507035 | 0.77 | PPARA (0.42) | PPARAPPARGPPARDPOLBLMNA | |
| SCHEMBL4904168 | 0.76 | LMNA (0.56) | PPARAPPARGPPARDPOLBLMNA | |
| SCHEMBL4899895 | 0.75 | PPARG (0.50) | PPARAPPARGPPARDPOLBLMNA | |
| SCHEMBL4906394 | 0.74 | LMNA (0.41) | POLBLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288340-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER INC | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288340-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PPARA, PPARG, PPARD | PPARA 1/4885PPARG 2/4885PPARD 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.