Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.46 |
| ▸ | GRK6 | P43250 | 1/20 | 0.44 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.42 |
| ▸ | PIM1 | P11309 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.42 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650707 | 1.00 | MEN1 (0.48) | MEN1KMT2AMAPTNPSR1L3MBTL1 | |
| SCHEMBL651445 | 0.91 | MEN1 (0.58) | MEN1KMT2AMAPTNPSR1L3MBTL1 | |
| SCHEMBL651446 | 0.91 | MEN1 (0.58) | MEN1KMT2AMAPTNPSR1L3MBTL1 | |
| SCHEMBL649099 | 0.88 | MAPT (0.62) | MEN1KMT2AMAPTNPSR1L3MBTL1 | |
| SCHEMBL649100 | 0.88 | MAPT (0.62) | MEN1KMT2AMAPTNPSR1L3MBTL1 | |
| SCHEMBL649023 | 0.84 | MEN1 (0.46) | MEN1KMT2AMAPTNPSR1L3MBTL1 | |
| SCHEMBL649022 | 0.84 | MEN1 (0.46) | MEN1KMT2AMAPTNPSR1L3MBTL1 | |
| SCHEMBL652067 | 0.83 | MEN1 (0.46) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL652068 | 0.83 | MEN1 (0.46) | MEN1KMT2AMAPTL3MBTL1MAPK1 | |
| SCHEMBL653880 | 0.81 | MAPT (0.48) | MEN1KMT2AMAPTNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018389-B1 | HAFNIUM COMPLEXES OF CARBAZOLYL SUBSTITUTED IMIDAZOLE LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-03-09 | — | — | EP | disclosed |
| EP-2018390-B1 | ORTHO-METALLATED HAFNIUM COMPLEXES OF IMIDAZOLE LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-03-09 | — | — | EP | disclosed |
| EP-2021381-B1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-12-23 | — | — | EP | disclosed |
| US-9181368-B2 | High activity, low molecular weight olefin polymerization process | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140066585-A1 | HIGH ACTIVITY, LOW MOLECULAR WEIGHT OLEFIN POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-03-06 | — | — | US | disclosed |
| US-8604145-B2 | High activity, low molecular weight olefin polymerization process | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-12-10 | — | — | US | disclosed |
| US-8580976-B2 | Process for preparing A 2-substituted benzofuran-3-yl borate ester | DOW GLOBAL TECHNOLOGIES, LLC (US) | 2013-11-12 | — | — | US | disclosed |
| US-20130102789-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130102795-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-25 | — | — | US | disclosed |
| US-20130085284-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-04-04 | — | — | US | disclosed |
| WO-2000002930-A1 | A CATALYST COMPOSITION AND METHODS FOR ITS PREPARATION AND USE IN A POLYMERIZATION PROCESS | UNIVATION TECHNOLOGIES LLC (US) | 2000-01-20 | — | — | WO | disclosed |
| EP-0965601-A1 | Mixed catalyst composition for the production of olefin polymers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-12-22 | — | — | EP | disclosed |
| WO-1999061486-A1 | CATALYST DELIVERY METHOD AND CATALYST FEEDER | UNIVATION TECHNOLOGIES LLC (US) | 1999-12-02 | — | — | WO | disclosed |
| EP-0952996-A1 | METHOD OF CONTROLLING OLEFIN POLYMERIZATION CATALYST COMPOSITION ACTIVITY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0952995-A1 | OLEFIN POLYMERIZATION CATALYST COMPOSITION HAVING INCREASED ACTIVITY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-11-03 | — | — | EP | disclosed |
| EP-0942009-A2 | Reduced sheeting in single-site and single-site like polymerization by employing a chromium containing compound | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (a Delaware corporation) (US) | 1999-09-15 | — | — | EP | disclosed |
| US-5912202-A | CONTACTING OUTSIDE OF POLYMERIZATION REACTOR A SINGLE SITE CATALYST PRECURSOR WITH AN ACTIVATING COCATALYST BEFORE, DURING, OR AFTER CONTACTING THE SINGLE SITE CATALYST PRECURSOR WITH A WEAKLY COORDINATING ELECTRON DONOR SUCH AS 1-HEXENE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-06-15 | — | — | US | disclosed |
| WO-1998037103-A1 | PRODUCTION OF POLYOLEFINS OF CONTROLLED PARTICLE SIZE | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-08-27 | — | — | WO | disclosed |
| WO-1998030608-A1 | METHOD OF CONTROLLING OLEFIN POLYMERIZATION CATALYST COMPOSITION ACTIVITY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
| WO-1998030606-A1 | OLEFIN POLYMERIZATION CATALYST COMPOSITION HAVING INCREASED ACTIVITY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1998-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102795-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | HACL2, MIA3, HAO2 | MEN1 4102/4885KMT2A 3907/4885MAPT 2920/4885 |
| US-20130085284-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | HACL2, MIA3, HAO2 | MEN1 4102/4885KMT2A 3907/4885MAPT 2920/4885 |
| US-20130102789-A1 | HAFNIUM COMPLEXES OF HETEROCYCLIC ORGANIC LIGANDS | HACL2, MIA3, HAO2 | MEN1 4102/4885KMT2A 3907/4885MAPT 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.