Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 5/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC2A4 | P14672 | 3/20 | 0.37 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512171 | 0.89 | SSTR4 (0.41) | MMP2MMP9MMP8MMP13F2 | |
| SCHEMBL17726555 | 0.84 | SLC2A1 (0.48) | SLC2A1F2MAOBLMNAKDM4E | |
| SCHEMBL109277 | 0.84 | SSTR4 (0.44) | MMP2MMP9MMP8MMP13SSTR4 | |
| SCHEMBL29563667 | 0.84 | SSTR4 (0.44) | MMP2MMP9MMP8MMP13SSTR4 | |
| SCHEMBL6508209 | 0.83 | SSTR4 (0.44) | MMP2MMP9MMP8MMP13SSTR4 | |
| SCHEMBL16468138 | 0.81 | SLC2A1 (0.41) | SLC2A1MTNR1AMTNR1BF2BCHE | |
| SCHEMBL6510214 | 0.80 | SSTR4 (0.57) | MMP2MMP9MMP8MMP13SSTR4 | |
| SCHEMBL23081661 | 0.79 | SSTR4 (0.45) | MMP2MMP9MMP8MMP13SSTR4 | |
| SCHEMBL16467891 | 0.78 | SLC2A1 (0.50) | SLC2A1MAOBACHELMNAKDM4E | |
| SCHEMBL2531765 | 0.75 | SSTR4 (0.39) | MMP2MMP9MMP8MMP13SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014588-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY | ARGENTA DISCOVERY LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |