Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.35 |
| ▸ | SLC2A8 | Q9NY64 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512171 | 0.89 | SSTR4 (0.41) | SSTR4KDM4ELMNAMMP2MMP9 | |
| SCHEMBL29563667 | 0.85 | SSTR4 (0.44) | SSTR4MMP2MMP9MMP8MMP13 | |
| SCHEMBL109277 | 0.85 | SSTR4 (0.44) | SSTR4MMP2MMP9MMP8MMP13 | |
| SCHEMBL6507203 | 0.83 | SLC2A1 (0.41) | SSTR4KDM4ELMNAMMP2MMP9 | |
| SCHEMBL5153408 | 0.82 | HDAC3 (0.46) | LTA4HSMN1; SMN2KDM4ELMNA | |
| SCHEMBL6510214 | 0.82 | SSTR4 (0.57) | SSTR4MMP2MMP9MMP8MMP13 | |
| SCHEMBL23081661 | 0.81 | SSTR4 (0.45) | SSTR4MMP2MMP9MMP8MMP13 | |
| SCHEMBL14005309 | 0.78 | SSTR4 (0.39) | SSTR4SMN1; SMN2KDM4ELMNAGRM2 | |
| SCHEMBL14030942 | 0.78 | SLC2A4 (0.40) | SSTR4GRM2SLC2A4SLC2A8 | |
| SCHEMBL3899039 | 0.78 | SSTR4 (0.47) | SSTR4SMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014588-A1 | SUBSTITUTED THIENYL-HYDROXAMIC ACIDS HAVING HISTONE DEACETYLASE ACTIVITY | ARGENTA DISCOVERY LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |