Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14432062 | 0.85 | PSEN1 (0.41) | GAAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18477541 | 0.82 | PSEN1 (0.42) | GAAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25370190 | 0.82 | PSEN1 (0.34) | GAAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2670354 | 0.81 | PSEN1 (0.36) | GAAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2082222 | 0.79 | PSEN1 (0.36) | GAAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2082224 | 0.79 | PSEN1 (0.36) | GAAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL6509736 | 0.79 | HTT (0.45) | EPHX1KMT2A | |
| SCHEMBL2082309 | 0.78 | KMT2A (0.35) | GAAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2082308 | 0.78 | KMT2A (0.35) | GAAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8570166 | 0.78 | KMT2A (0.35) | GAAPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047253-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |