Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.30 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7556945 | 0.98 | HTT (0.44) | HTTEPHX1KDM4EKMT2AHRH3 | |
| SCHEMBL11801116 | 0.85 | HTT (0.58) | HTTEPHX1KDM4EKMT2AKIF11 | |
| SCHEMBL7046975 | 0.83 | HTT (0.56) | HTTKDM4EKMT2AKIF11CHRM5 | |
| Hydrochloric Acid SCHEMBL30853118 | 0.82 | HTT (0.37) | HTTEPHX1KDM4EKMT2AALOX15 | |
| SCHEMBL6507225 | 0.79 | GAA (0.40) | EPHX1KMT2A | |
| SCHEMBL23051874 | 0.77 | HTT (0.43) | HTTEPHX1 | |
| SCHEMBL19069845 | 0.77 | HTT (0.43) | HTTEPHX1 | |
| Hydrochloric Acid SCHEMBL7561967 | 0.71 | HTT (0.35) | HTTEPHX1KDM4EKMT2AHRH3 | |
| SCHEMBL23573256 | 0.70 | P2RX7 (0.34) | HTTEPHX1KDM4EMAPT | |
| SCHEMBL16790650 | 0.69 | HTT (0.38) | HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005019224-A2 | NOVEL ANTIINFECTIVE COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2005-03-03 | — | — | WO | claimed |
| WO-2005047253-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |
| WO-2005019224-A2 | NOVEL ANTIINFECTIVE COMPOUNDS | CADILA HEALTHCARE LIMITED (IN) | 2005-03-03 | — | — | WO | disclosed |