Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.40 |
| ▸ | PTPRC | P08575 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507339 | 0.82 | PTPN1 (0.37) | PTPN1PTPN2PTPRC | |
| SCHEMBL4118684 | 0.77 | PTPN1 (0.46) | PTPN1PTPN2PTPRCPTGDR2 | |
| SCHEMBL4119518 | 0.75 | DYRK1A (0.51) | PTPN1PTPN2PTPRC | |
| SCHEMBL4132071 | 0.75 | PTPN1 (0.42) | PTPN1PTPN2PTPRC | |
| SCHEMBL4120133 | 0.74 | PTPN1 (0.49) | PTPN1PTPN2PTPRC | |
| SCHEMBL4127309 | 0.71 | PTPN1 (0.49) | PTPN1PTPN2PTPRC | |
| SCHEMBL13926050 | 0.71 | MCL1 (0.57) | PTPN1PTPN2PTPRCPTGDR2MAPT | |
| SCHEMBL4132062 | 0.70 | PTPN1 (0.47) | PTPN1PTPN2PTPRC | |
| SCHEMBL4125935 | 0.70 | PTPN1 (0.45) | PTPN1PTPN2PTPRC | |
| SCHEMBL4125928 | 0.70 | PTPN1 (0.45) | PTPN1PTPN2PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005081960-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE 1B | WYETH (US) | 2005-09-09 | — | — | WO | disclosed |