Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12203268 | 0.81 | ALDH1A1 (0.42) | FFAR1ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8304192 | 0.81 | FFAR1 (0.43) | FFAR1PTGDR2IDO1ALDH1A1KDM4E | |
| SCHEMBL5542869 | 0.81 | FFAR1 (0.43) | FFAR1PTGDR2IDO1ALDH1A1KDM4E | |
| SCHEMBL21974241 | 0.81 | FFAR1 (0.43) | FFAR1PTGDR2IDO1ALDH1A1AR | |
| SCHEMBL17274316 | 0.80 | CYP3A4 (0.58) | FFAR1PTGDR2ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL30515632 | 0.79 | CYP1A2 (0.44) | PTGDR2ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL6449051 | 0.79 | CYP1A2 (0.44) | PTGDR2ALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL11236978 | 0.77 | FFAR1 (0.40) | FFAR1PTGDR2IDO1ALDH1A1AR | |
| SCHEMBL4057890 | 0.77 | AR (0.48) | ALDH1A1GAAHTTAR | |
| SCHEMBL8902611 | 0.77 | FFAR1 (0.40) | FFAR1PTGDR2IDO1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005015400-A | TRIFLUOROMETHYLCINNAMYL ALCOHOL AND ITS MANUFACTURING METHOD | CENTRAL GLASS CO LTD | 2005-01-20 | — | — | JP | disclosed |
| US-4322432-A | Cyclopropanecarboxylic acid alkynyl esters, processes for producing them, and their use as pesticides | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |