Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.43 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.43 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | BCL6 | P41182 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15146279 | 0.87 | AURKA (0.47) | KDRSCN9AMEN1KMT2APIN1 | |
| SCHEMBL2411693 | 0.87 | AURKA (0.53) | KDRMEN1KMT2APIN1TTBK1 | |
| SCHEMBL16012862 | 0.87 | MEN1 (0.48) | NR1I2AHRMKNK1MEN1KMT2A | |
| SCHEMBL16264851 | 0.87 | MEN1 (0.45) | NR1I2AHRMEN1KMT2APIN1 | |
| SCHEMBL16012244 | 0.87 | CCNT1 (0.43) | ADORA3SLC6A2PDE4AKDRNR1I2 | |
| SCHEMBL24654519 | 0.86 | PIN1 (0.57) | KDRMEN1KMT2APIN1GAA | |
| SCHEMBL15147773 | 0.83 | MAPT (0.53) | MEN1KMT2ATTBK1TTBK2GAA | |
| SCHEMBL16022207 | 0.81 | EGFR (0.50) | KDRPIN1EGFR | |
| SCHEMBL14764555 | 0.79 | CTSC (0.54) | SCN9ATTBK1TTBK2KCNH2SCN5A | |
| SCHEMBL655628 | 0.79 | AURKA (0.54) | KDRKMT2ABCL6STK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061505-A1 | BICYCLIC IMIDAZOLYL PYRIMIDIN-4-ONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |