Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | GFER | P55789 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15653140 | 0.82 | MAPT (0.67) | MAPTALDH1A1GFERTDP1LMNA | |
| SCHEMBL17265648 | 0.82 | ALDH1A1 (0.77) | MAPTALDH1A1GFERTDP1LMNA | |
| SCHEMBL159281 | 0.80 | MAPT (0.68) | MAPTALDH1A1GFERTDP1LMNA | |
| SCHEMBL20591936 | 0.79 | ALDH1A1 (0.48) | MAPTALDH1A1GFERTDP1LMNA | |
| SCHEMBL1725003 | 0.79 | ALDH1A1 (0.59) | MAPTALDH1A1GFERTDP1LMNA | |
| SCHEMBL27908174 | 0.78 | MAPT (0.58) | MAPTALDH1A1GFERTDP1LMNA | |
| SCHEMBL521899 | 0.78 | MAPT (0.55) | MAPTALDH1A1GFERTDP1LMNA | |
| SCHEMBL6508996 | 0.78 | ALDH1A1 (0.61) | MAPTALDH1A1LMNAMAPK1GAA | |
| SCHEMBL3027517 | 0.78 | MAPT (0.57) | MAPTALDH1A1GFERTDP1LMNA | |
| Hydrochloric Acid SCHEMBL1726121 | 0.78 | ALDH1A1 (0.57) | MAPTALDH1A1GFERTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082892-A2 | TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2005-09-09 | — | — | WO | disclosed |