Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.59 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3924113 | 0.92 | ADRB2 (0.57) | ADRB2CHRM3ALDH1A1KDM4EMAPT | |
| SCHEMBL6533350 | 0.89 | ADRB2 (0.60) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL6533863 | 0.87 | ADRB2 (0.58) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6506204 | 0.86 | ADRB2 (0.78) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6531334 | 0.86 | ADRB2 (0.62) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6531338 | 0.86 | ADRB2 (0.62) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6533625 | 0.85 | ADRB2 (0.56) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6506682 | 0.85 | ADRB2 (0.59) | ADRB2ADRB1ADRB3 | |
| SCHEMBL6533241 | 0.85 | ADRB2 (0.55) | ADRB2CHRM3ADRB1 | |
| SCHEMBL6528643 | 0.84 | ADRB2 (0.59) | ADRB2CHRM3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |