Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.53 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | CISD1 | Q9NZ45 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507951 | 0.84 | PIM1 (0.52) | PIM1PIM2MAOAMAOBMEN1 | |
| SCHEMBL6532952 | 0.84 | PIM1 (0.52) | PIM1PIM2MAOAMAOBMEN1 | |
| SCHEMBL6528290 | 0.80 | MAPT (0.38) | — | |
| SCHEMBL6510045 | 0.73 | MGAM (0.56) | PIM1PIM2MAOAMAOBCISD1 | |
| SCHEMBL1250576 | 0.72 | PIM1 (1.00) | PIM1PIM2MAOAMAOBCISD1 | |
| SCHEMBL2544417 | 0.72 | PIM1 (1.00) | PIM1PIM2MAOAMAOBCISD1 | |
| SCHEMBL1250573 | 0.72 | PIM1 (1.00) | PIM1PIM2MAOAMAOBCISD1 | |
| SCHEMBL6529791 | 0.72 | MGAM (0.48) | PIM1PIM2MAOAMAOBMEN1 | |
| SCHEMBL6529790 | 0.72 | MGAM (0.48) | PIM1PIM2MAOAMAOBMEN1 | |
| SCHEMBL6511845 | 0.71 | PIM1 (0.50) | PIM1PIM2MAOAMAOBIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |