Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.38 |
| ▸ | TSPO | P30536 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509090 | 0.80 | PTGER4 (0.44) | PTGER4TSPOALDH1A1 | |
| SCHEMBL6507697 | 0.80 | PIM1 (0.53) | — | |
| SCHEMBL16066019 | 0.73 | PTGER4 (0.68) | MAPTPTGER4TSPODNM1SMN1; SMN2 | |
| SCHEMBL30061939 | 0.73 | PTGER4 (0.68) | MAPTPTGER4TSPODNM1SMN1; SMN2 | |
| SCHEMBL13158817 | 0.70 | ALDH1A1 (0.40) | MAPTPTGER4SMN1; SMN2JAK3ALDH1A1 | |
| SCHEMBL29392880 | 0.70 | ALDH1A1 (0.40) | MAPTPTGER4SMN1; SMN2JAK3ALDH1A1 | |
| SCHEMBL29178204 | 0.70 | CYP2A6 (0.41) | ALDH1A1 | |
| SCHEMBL17515011 | 0.68 | ALDH1A1 (0.42) | MAPTPTGER4SMN1; SMN2JAK3ALDH1A1 | |
| SCHEMBL10670569 | 0.68 | TSPO (0.50) | MAPTPTGER4TSPODNM1SMN1; SMN2 | |
| SCHEMBL14689815 | 0.68 | MAPT (0.50) | MAPTTSPODNM1SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100331-A2 | ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2005-10-27 | — | — | WO | disclosed |