Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 6/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506105 | 0.88 | PPARG (0.46) | PPARGPPARAESR1ESR2MIF | |
| SCHEMBL6504116 | 0.86 | MIF (0.50) | PPARGPPARAESR1ESR2MDM4 | |
| SCHEMBL6504111 | 0.86 | MIF (0.50) | PPARGPPARAESR1ESR2MDM4 | |
| SCHEMBL6510871 | 0.85 | PPARG (0.51) | PPARGPPARAMAOB | |
| SCHEMBL6533647 | 0.84 | MIF (0.41) | PPARGPPARAESR1ESR2MAOB | |
| SCHEMBL6505172 | 0.82 | ESR1 (0.47) | PPARGPPARAESR1ESR2MDM4 | |
| SCHEMBL6510664 | 0.81 | ESR1 (0.46) | PPARGPPARARAB9AESR1ESR2 | |
| SCHEMBL6507933 | 0.80 | ESR1 (0.50) | PPARGPPARAESR1ESR2MDM4 | |
| SCHEMBL6510040 | 0.80 | ESR1 (0.50) | PPARGPPARAESR1ESR2MDM4 | |
| SCHEMBL6509594 | 0.79 | ESR1 (0.47) | PPARGPPARAESR1ESR2MDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |