Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.51 |
| ▸ | PPARA | Q07869 | 11/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511136 | 0.90 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL6511131 | 0.90 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL6506105 | 0.88 | PPARG (0.46) | PPARGPPARACA12CA7CA9 | |
| SCHEMBL6507734 | 0.85 | PPARG (0.43) | PPARGPPARAMAOB | |
| SCHEMBL6504116 | 0.82 | MIF (0.50) | PPARGPPARA | |
| SCHEMBL6504111 | 0.82 | MIF (0.50) | PPARGPPARA | |
| SCHEMBL6384666 | 0.78 | NLRP3 (0.51) | PPARGPPARANLRP3 | |
| SCHEMBL6533647 | 0.77 | MIF (0.41) | PPARGPPARAS1PR1MAOBNOS3 | |
| SCHEMBL2564195 | 0.77 | NLRP3 (0.48) | PPARGPPARANLRP3 | |
| SCHEMBL6505172 | 0.77 | ESR1 (0.47) | PPARGPPARANLRP3S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |