Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915488 | 0.93 | ADRB2 (0.62) | ADRB2ADRB1SRCCHRM3MAPK1 | |
| SCHEMBL6511118 | 0.93 | ADRB2 (0.68) | ADRB2ADRB1CHRM3RAB9A | |
| SCHEMBL6506204 | 0.90 | ADRB2 (0.78) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6529257 | 0.89 | ADRB2 (0.59) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6528102 | 0.87 | ADRB2 (0.68) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6507640 | 0.85 | ADRB2 (0.69) | ADRB2ADRB1CHRM3 | |
| SCHEMBL3921775 | 0.85 | ADRB2 (0.65) | ADRB2ADRB1CHRM3RAB9A | |
| SCHEMBL13840738 | 0.83 | ADRB2 (0.74) | ADRB2ADRB1CHRM3 | |
| SCHEMBL3915477 | 0.83 | ADRB2 (0.74) | ADRB2ADRB1CHRM3 | |
| SCHEMBL6531425 | 0.83 | ADRB2 (0.59) | ADRB2ADRB1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |