Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516272 | 0.88 | ATM (0.41) | ATMFFAR4MEP1BALDH1A1L3MBTL1 | |
| SCHEMBL6511195 | 0.87 | NPC1 (0.42) | ATMFFAR4ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL6508460 | 0.85 | HTR2C (0.36) | MAOAMEP1BL3MBTL1FFAR1SMN1; SMN2 | |
| SCHEMBL6511522 | 0.83 | GAA (0.40) | ATMMAOAMEP1BALDH1A1GAA | |
| SCHEMBL6533581 | 0.83 | POLB (0.38) | ATMFFAR4MEP1BALDH1A1SMN1; SMN2 | |
| SCHEMBL6531739 | 0.82 | ATM (0.38) | ATMFFAR4MEP1BALDH1A1GAA | |
| SCHEMBL6532728 | 0.82 | ATM (0.39) | ATMFFAR4MEP1BNR1H4 | |
| SCHEMBL6533389 | 0.81 | MAPT (0.41) | FFAR4MEP1BFFAR1 | |
| SCHEMBL6512333 | 0.79 | SLC2A1 (0.45) | FFAR4FFAR1 | |
| SCHEMBL6508922 | 0.79 | ATM (0.35) | ATMFFAR4MEP1BALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |