Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PPM1D | O15297 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6518913 | 0.88 | NPC1 (0.50) | GAAALDH1A1L3MBTL1NPC1FAAH | |
| SCHEMBL6512333 | 0.85 | SLC2A1 (0.45) | FFAR1 | |
| SCHEMBL6533389 | 0.83 | MAPT (0.41) | MEP1BFFAR1 | |
| SCHEMBL6512010 | 0.83 | LTB4R (0.42) | L3MBTL1NPC1MAOAMEN1KMT2A | |
| SCHEMBL6533750 | 0.82 | GAA (0.43) | GAAALDH1A1L3MBTL1NPC1FAAH | |
| SCHEMBL6515075 | 0.82 | GAA (0.41) | GAAALDH1A1L3MBTL1NPC1FAAH | |
| SCHEMBL6511525 | 0.80 | LTB4R (0.40) | OPRM1OPRD1OPRK1MEP1BFFAR1 | |
| SCHEMBL6511514 | 0.79 | OPRM1 (0.37) | HPGDMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL6509240 | 0.79 | PPARA (0.41) | OPRM1OPRD1OPRK1FFAR1 | |
| SCHEMBL6508460 | 0.79 | HTR2C (0.36) | L3MBTL1HPGDMAOAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |