SCHEMBL6507790

SCHEMBL6507790

O=C(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS9 O00182 1/20 0.61
LGALS1 P09382 1/20 0.61
LGALS3 P17931 1/20 0.61
LGALS7; LGALS7B P47929 1/20 0.61
MAOB P27338 1/20 0.58
SYNJ2 O15056 2/20 0.49
KDM4E B2RXH2 1/20 0.49
ABL1 P00519 1/20 0.49
ALPL P05186 1/20 0.49
POLB P06746 1/20 0.49
ALPI P09923 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
ALPG P10696 1/20 0.49
PABPC1 P11940 1/20 0.49
RECQL P46063 1/20 0.49
GALK1 P51570 1/20 0.49
CASP7 P55210 1/20 0.49
CASP6 P55212 1/20 0.49
MCL1 Q07820 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7138693 1.00 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL28162884 1.00 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL6570199 1.00 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL27639803 1.00 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL7144990 1.00 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL7141014 1.00 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL6570202 1.00 LGALS9 (0.61) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL8762538 0.98 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL10524702 0.98 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB
SCHEMBL9451232 0.98 LGALS9 (0.60) LGALS9LGALS1LGALS3LGALS7; LGALS7BMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005016878-A2 METHODS FOR THE PREPARATION OF 5-FLUORO-PYRROLO[2,3-d]PYRIMIDINE COMPOUNDS ISIS PHARMACEUTICALS, INC. (US) 2005-02-24 WO claimed
CN-108570078-A A method of preparing three-O- benzoyls-β of 1-O- acetyl group -2,3,5--D-RIBOSE 荆门医药工业技术研究院 2018-09-25 CN disclosed
CN-103570784-A Synthesis method of 2'-FANA (2'-deoxy-2'-fluoro-beta-D-arabino nucleic acid) series fluoro-oligonucleotides ANHUI RUISAI BIOCHEMICAL TECHNOLOGY CO LTD 2014-02-12 CN disclosed
CN-101531695-A Method for synthesizing fluoro-oligonucleotide for preparing siRNA ZHENGZHOU RUISAI TECHNOLOGY AN 2009-09-16 CN disclosed
CN-1065462-A Replace 2 ', 3 '-dideoxy-5-trifluoromethyl uridine diphosphate glycoside, their preparation method and they application aspect medical BAYER AG (DE) 1992-10-21 CN disclosed
CN-85109195-A The preparation of Imidazopyridazine derivative and application 1986-11-05 CN disclosed