Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 3/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13374712 | 0.89 | BCHE (0.50) | BCHECA12CA1CA9ALDH1A1 | |
| SCHEMBL6035952 | 0.89 | BCHE (0.50) | BCHECA12CA1CA9ALDH1A1 | |
| SCHEMBL27696190 | 0.89 | BCHE (0.50) | BCHECA12CA1CA9ALDH1A1 | |
| SCHEMBL28089034 | 0.87 | BCHE (0.46) | BCHECA12CA1CA9PLA2G2A | |
| SCHEMBL28089035 | 0.87 | BCHE (0.46) | BCHECA12CA1CA9PLA2G2A | |
| SCHEMBL18944050 | 0.85 | MMP8 (0.46) | BCHEPLA2G2APLA2G5MMP8 | |
| SCHEMBL10454099 | 0.85 | MMP8 (0.46) | BCHEPLA2G2APLA2G5MMP8 | |
| SCHEMBL18944204 | 0.85 | MMP8 (0.46) | BCHEPLA2G2APLA2G5MMP8 | |
| SCHEMBL6036734 | 0.85 | MMP8 (0.46) | BCHEPLA2G2APLA2G5MMP8 | |
| Hydrochloric Acid SCHEMBL7765619 | 0.84 | MMP8 (0.45) | BCHEPLA2G2APLA2G5MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003103-A2 | 2, 4, 6-TRI-SUBSTITUTED 6-MEMBERED HETEROCYCLES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003103-A2 | 2, 4, 6-TRI-SUBSTITUTED 6-MEMBERED HETEROCYCLES AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | ASTRAZENECA AB (SE) | 2005-01-13 | — | — | WO | disclosed |