Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 17/20 | 0.46 |
| ▸ | CA2 | P00918 | 17/20 | 0.46 |
| ▸ | CA4 | P22748 | 10/20 | 0.46 |
| ▸ | CA5A | P35218 | 5/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 8/20 | 0.36 |
| ▸ | CA7 | P43166 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA6 | P23280 | 4/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.36 |
| ▸ | CA3 | P07451 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CA11 | O75493 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9731492 | 0.82 | CA1 (0.43) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL4639363 | 0.82 | CA1 (0.52) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11377949 | 0.81 | CA2 (0.38) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11386535 | 0.79 | CA1 (0.37) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL3902164 | 0.79 | CA2 (0.54) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11378008 | 0.77 | CA2 (0.43) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11383964 | 0.77 | CA1 (0.40) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11380580 | 0.77 | CA2 (0.37) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL3902865 | 0.75 | MAPT (0.52) | CA1CA2CA4CA9THRB | |
| SCHEMBL3902863 | 0.75 | CA2 (0.38) | CA1CA2CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005014554-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS MAPKAP KINASE MODULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-17 | — | — | WO | claimed |
| US-4281121-A | 1,3,4-Thiadiazole-2-carboxylic acid derivatives, process for making the same and fungicidal and nematocidal compositions containing same | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-07-28 | — | — | US | claimed |
| WO-2005014554-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS MAPKAP KINASE MODULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-17 | — | — | WO | disclosed |
| US-4281121-A | 1,3,4-Thiadiazole-2-carboxylic acid derivatives, process for making the same and fungicidal and nematocidal compositions containing same | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-07-28 | — | — | US | disclosed |
| US-4279907-A | 1,3,4-Thiadiazole-2-carboxylic acid derivatives, process for making the same and fungicidal and nematocidal compositions containing same | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |