Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 20/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 18/20 | 0.79 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506235 | 0.84 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6505398 | 0.83 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6689722 | 0.83 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6509445 | 0.82 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6508389 | 0.81 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6528086 | 0.81 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6534038 | 0.81 | ADORA2B (0.86) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6508109 | 0.80 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6506298 | 0.80 | ADORA2B (0.78) | ADORA2BADORA2AADORA1 | |
| SCHEMBL6507101 | 0.79 | ADORA2B (1.00) | ADORA2BADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005090309-A1 | 1,2-DIHYDROQUINOLINE DERIVATIVES AND METHOD FOR USING THE SAME TO TREAT HIV INFECTION | WYETH (US) | 2005-09-29 | — | — | WO | disclosed |
| US-20050070558-A1 | 6-Phenyldihydropyrrolopyrimidinedione derivatives | ALMIRALL PRODESFARMA S.A. (ES) | 2005-03-31 | — | — | US | disclosed |
| EP-0742810-A1 | RUBBER COMPOUNDING FORMULATION AND METHOD | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1996-11-20 | — | — | EP | disclosed |
| WO-1995021214-A1 | RUBBER COMPOUNDING FORMULATION AND METHOD | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1995-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070558-A1 | 6-Phenyldihydropyrrolopyrimidinedione derivatives | ADORA1, ADORA2A, P2RY10 | ADORA2B 4/4885ADORA2A 2/4885ADORA1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.