Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 12/20 | 0.58 |
| ▸ | KDR | P35968 | 16/20 | 0.46 |
| ▸ | MST1R | Q04912 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | TPO | P07202 | 1/20 | 0.39 |
| ▸ | EPX | P11678 | 1/20 | 0.39 |
| ▸ | LPO | P22079 | 1/20 | 0.39 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13663028 | 0.89 | MET (0.53) | METKDRMST1RFLT1 | |
| SCHEMBL6509695 | 0.88 | MET (0.57) | METKDRMST1RMPOTPO | |
| SCHEMBL3567643 | 0.84 | MET (0.49) | METKDRMST1R | |
| SCHEMBL8139732 | 0.80 | MET (0.47) | METKDRMST1R | |
| SCHEMBL307866 | 0.79 | MET (0.57) | METKDRMST1RFLT1 | |
| SCHEMBL4307653 | 0.79 | MET (0.47) | METKDRMST1RFLT1 | |
| SCHEMBL5838512 | 0.79 | MET (0.48) | METKDRMST1RFLT1 | |
| SCHEMBL4708197 | 0.79 | KDR (0.56) | METKDRMST1RFLT1 | |
| SCHEMBL13254388 | 0.78 | MET (0.49) | METKDRMST1RFLT1 | |
| SCHEMBL4299410 | 0.76 | MET (0.46) | METKDRMST1RFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005121125-A1 | ETHER-LINKED HETEROARYL COMPOUNDS | PFIZER INC. (US) | 2005-12-22 | — | — | WO | disclosed |