Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.72 |
| ▸ | HTR2B | P41595 | 3/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.53 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507506 | 1.00 | HTR2C (0.72) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6510239 | 0.97 | HTR2C (0.77) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6508031 | 0.97 | HTR2C (0.77) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL30001584 | 0.96 | HTR2C (0.76) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6518480 | 0.89 | HTR2C (0.68) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6510388 | 0.88 | HTR2C (0.72) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6507511 | 0.85 | HTR2C (0.77) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6511035 | 0.84 | HTR2C (0.73) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6508988 | 0.84 | HTR2C (0.73) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL30001565 | 0.84 | HTR2C (0.80) | HTR2CHTR2BHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | disclosed |