Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.73 |
| ▸ | HTR2B | P41595 | 3/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508988 | 1.00 | HTR2C (0.73) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL15833076 | 0.92 | HTR2C (0.61) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6511003 | 0.90 | HTR2C (0.73) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL30604551 | 0.89 | HTR2C (0.77) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| Hydrochloric Acid SCHEMBL30002187 | 0.88 | HTR2C (0.75) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL7314615 | 0.88 | HTR2C (0.60) | HTR2CHTR2BKDM4E | |
| SCHEMBL6511622 | 0.87 | S1PR1 (0.57) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6510804 | 0.87 | S1PR1 (0.57) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6508031 | 0.87 | HTR2C (0.77) | HTR2CHTR2BHDAC3HDAC1HDAC2 | |
| SCHEMBL6510239 | 0.87 | HTR2C (0.77) | HTR2CHTR2BHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040108-A1 | PROLINAMIDE DERIVATIVES AS SODIUM AND/OR CALCIUM CHANNEL BLOCKERS OR SELECTIVE MAO-B INHIBITORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-05-06 | — | — | WO | claimed |