SCHEMBL6508870

SCHEMBL6508870

CCON=c1sc2cc(N3CC(CNC(=O)CC)OC3=O)ccc2n1C

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.43
MAOA P21397 2/20 0.43
LMNA P02545 1/20 0.43
PTGS1 P23219 1/20 0.43
CALML3 P27482 1/20 0.43
SDHA P31040 1/20 0.43
F10 P00742 17/20 0.43
F2 P00734 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6508866 1.00 MAOB (0.43) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6532575 0.92 MAOA (0.52) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6513198 0.92 F10 (0.44) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6513194 0.92 F10 (0.44) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6532583 0.92 MAOA (0.52) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6532578 0.92 MAOA (0.52) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6510924 0.92 MAOA (0.43) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6510916 0.92 MAOA (0.43) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6516109 0.91 MAOA (0.49) MAOBMAOALMNAPTGS1CALML3
SCHEMBL6515805 0.89 F10 (0.45) MAOBMAOALMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005082900-A2 OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2005-09-09 WO claimed
WO-2005082900-A2 OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS PHARMACIA & UPJOHN COMPANY LLC (US) 2005-09-09 WO disclosed