Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 20/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509264 | 0.87 | ADORA2B (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6502217 | 0.86 | ADORA2A (0.76) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6503696 | 0.84 | ADORA2B (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6512027 | 0.84 | ADORA2B (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6509136 | 0.83 | ADORA2B (1.00) | ADORA2AADORA2B | |
| SCHEMBL6506951 | 0.83 | ADORA2B (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6508242 | 0.82 | ADORA2B (1.00) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6509624 | 0.82 | ADORA2B (0.74) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6510093 | 0.82 | ADORA2A (0.77) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL6509609 | 0.82 | ADORA2B (0.76) | ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070558-A1 | 6-Phenyldihydropyrrolopyrimidinedione derivatives | ALMIRALL PRODESFARMA S.A. (ES) | 2005-03-31 | — | — | US | disclosed |
| US-20050043313-A1 | Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2005-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070558-A1 | 6-Phenyldihydropyrrolopyrimidinedione derivatives | ADORA1, ADORA2A, P2RY10 | ADORA2A 2/4885ADORA2B 4/4885ADORA3 6/4885 |
| US-20050043313-A1 | Substituted polycyclic aryl and heteroaryl pyrazinones useful for selective inhibition of the coagulation cascade | TFPI, TFPI2, PLAT | ADORA2A 4078/4885ADORA2B 3136/4885ADORA3 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.