Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893076 | 1.00 | GRM8 (0.47) | GRM8GRM6GRM4MAPTMEN1 | |
| SCHEMBL6830994 | 0.83 | GRM8 (0.49) | GRM8GRM6GRM4MAPTMEN1 | |
| SCHEMBL22339025 | 0.80 | SLC1A3 (0.51) | GRM8GRM6GRM4MAPTMEN1 | |
| SCHEMBL22303821 | 0.80 | SLC1A3 (0.51) | GRM8GRM6GRM4MAPTMEN1 | |
| SCHEMBL22303091 | 0.80 | SLC1A3 (0.51) | GRM8GRM6GRM4MAPTMEN1 | |
| SCHEMBL7601233 | 0.80 | NPC1 (0.48) | MAPTMEN1KMT2ATDP1DPP4 | |
| SCHEMBL1913843 | 0.80 | SLC1A3 (0.51) | GRM8GRM6GRM4MAPTMEN1 | |
| SCHEMBL11052982 | 0.80 | ALDH1A1 (0.49) | MAPTMEN1KMT2ATDP1DPP4 | |
| SCHEMBL4694927 | 0.80 | ALDH1A1 (0.56) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL16781693 | 0.80 | ALDH1A1 (0.56) | MAPTMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953798-B1 | β-alanine derivates | CELLTECH R&D LIMITED (GB) | 2005-10-11 | — | — | US | disclosed |