Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.69 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509381 | 1.00 | MAPT (0.78) | MAPTSMN1; SMN2POLBNCOA1NCOA3 | |
| SCHEMBL14506304 | 0.78 | PTGS2 (0.78) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9192509 | 0.78 | PTGS2 (0.78) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL9192511 | 0.78 | PTGS2 (0.78) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL20024754 | 0.76 | GAA (0.66) | MAPTSMN1; SMN2POLBALDH1A1MAPK1 | |
| SCHEMBL6511560 | 0.76 | MAPT (0.67) | MAPTSMN1; SMN2POLBNCOA1NCOA3 | |
| SCHEMBL6511554 | 0.76 | MAPT (0.67) | MAPTSMN1; SMN2POLBNCOA1NCOA3 | |
| SCHEMBL6503720 | 0.76 | MAPT (0.57) | MAPTSMN1; SMN2POLBNCOA1NCOA3 | |
| SCHEMBL6503717 | 0.76 | MAPT (0.57) | MAPTSMN1; SMN2POLBNCOA1NCOA3 | |
| SCHEMBL24451139 | 0.75 | MAPT (0.72) | MAPTSMN1; SMN2POLBNCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050070558-A1 | 6-Phenyldihydropyrrolopyrimidinedione derivatives | ALMIRALL PRODESFARMA S.A. (ES) | 2005-03-31 | — | — | US | disclosed |
| WO-2005026139-A1 | NEMATICIDAL DIFLUOROALKENES | BAYER CROPSCIENCE AG (DE) | 2005-03-24 | — | — | WO | disclosed |
| EP-1465490-A2 | NEMATICIDAL TRIFLUOROBUTENYL IMIDAZOLE THIOETHER DERIVATIVES | Bayer CropScience AG (DE) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003106436-A1 | NEMATICIDAL TETRAZOLE-CONTAINING TRIFLUOROBUTENES | BAYER CROPSCIENCE AG (DE) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003049541-A2 | NEMATICIDAL TRIFLUOROBUTENYL IMIDAZOLE THIOETHER DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070558-A1 | 6-Phenyldihydropyrrolopyrimidinedione derivatives | ADORA1, ADORA2A, P2RY10 | MAPT 4800/4885SMN1; SMN2 3868/4885POLB 1758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.