Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 18/20 | 0.40 |
| ▸ | RAMP1 | O60894 | 4/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509436 | 1.00 | CALCRL (0.40) | CALCRLRAMP1CTSS | |
| SCHEMBL6509432 | 1.00 | CALCRL (0.40) | CALCRLRAMP1CTSS | |
| SCHEMBL6504866 | 0.89 | CALCRL (0.50) | CALCRLRAMP1 | |
| SCHEMBL6504879 | 0.89 | CALCRL (0.50) | CALCRLRAMP1 | |
| SCHEMBL6503913 | 0.89 | CALCRL (0.45) | CALCRLRAMP1CTSS | |
| SCHEMBL6506605 | 0.88 | CALCRL (0.48) | CALCRLRAMP1 | |
| SCHEMBL12881781 | 0.88 | CALCRL (0.39) | CALCRLRAMP1CTSS | |
| SCHEMBL12881783 | 0.87 | CALCRL (0.40) | CALCRLRAMP1CTSS | |
| SCHEMBL13046503 | 0.86 | CALCRL (0.37) | CALCRLRAMP1CTSS | |
| SCHEMBL14034846 | 0.86 | CALCRL (0.42) | CALCRLRAMP1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250763-A1 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250763-A1 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | CALCRL, CALCR, CALCA | CALCRL 1/4885RAMP1 46/4885CTSS 1357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.