Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 9/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510042 | 0.88 | ROCK2 (0.44) | NOTUMCYP2D6SLC6A2SLC6A4CYP2C19 | |
| SCHEMBL7812739 | 0.86 | ROCK2 (0.43) | NOTUMCYP2D6SLC6A2SLC6A4CYP2C19 | |
| SCHEMBL7813013 | 0.84 | SLC6A2 (0.64) | CYP2D6SLC6A2SLC6A4CYP2C19SLC6A3 | |
| SCHEMBL7819893 | 0.83 | SLC6A2 (0.50) | CYP2D6SLC6A2SLC6A4CYP2C19SLC6A3 | |
| SCHEMBL27547192 | 0.82 | ROCK2 (0.41) | NOTUMCYP2D6SLC6A2SLC6A4CYP2C19 | |
| SCHEMBL7806511 | 0.82 | SLC6A2 (0.51) | CYP2D6SLC6A2SLC6A4CYP2C19SLC6A3 | |
| SCHEMBL6530315 | 0.81 | CYP2D6 (0.50) | CYP2D6SLC6A2SLC6A4CYP2C19SLC6A3 | |
| SCHEMBL7816330 | 0.80 | SLC6A2 (0.52) | CYP2D6SLC6A2SLC6A4CYP2C19SLC6A3 | |
| SCHEMBL27570505 | 0.79 | SLC6A2 (0.48) | CYP2D6SLC6A2SLC6A4CYP2C19SLC6A3 | |
| SCHEMBL6512004 | 0.78 | NOTUM (0.46) | NOTUMCYP2D6CYP2C19AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005000824-A1 | LAZOLIDINE DERIVATIVES AS HERBICIDAL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | WO | disclosed |