Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067209 | 0.88 | HTT (0.48) | HTTNPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL6378334 | 0.81 | HTT (0.49) | HTTNPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL5069542 | 0.78 | MAPT (0.54) | HTTNPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL6512097 | 0.77 | HTT (0.43) | HTTNPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL11638099 | 0.76 | POLB (0.48) | HTTNPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL23579968 | 0.74 | MAPT (0.47) | HTTNPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL7653533 | 0.73 | MAPT (0.55) | HTTNPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL31256155 | 0.71 | MAPT (0.47) | HTTNPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL6108749 | 0.70 | GRM6 (0.47) | HTTMAPTPOLBALDH1A1LMNA | |
| SCHEMBL5953011 | 0.70 | MAPT (0.51) | HTTNPSR1MAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101063-A1 | Three-terminal field-controlled molecular devices | TOUR JAMES M (US) | 2005-05-12 | — | — | US | disclosed |
| WO-2002035580-A2 | THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES | MOLECULAR ELECTRONICS CORPORATION (US) | 2002-05-02 | — | — | WO | disclosed |