Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GALR2 | O43603 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509522 | 0.81 | HTT (0.43) | HTTPKML3MBTL1MAPTNPSR1 | |
| SCHEMBL14366637 | 0.80 | HTT (0.47) | HTTPKML3MBTL1MAPTNPSR1 | |
| SCHEMBL5072230 | 0.78 | ALDH1A1 (0.46) | HTTPKML3MBTL1MAPTNPSR1 | |
| SCHEMBL5069542 | 0.76 | MAPT (0.54) | HTTPKML3MBTL1MAPTNPSR1 | |
| SCHEMBL6421514 | 0.76 | CASP3 (0.48) | HTTMAPTNPSR1CA1CA2 | |
| SCHEMBL28923654 | 0.75 | HSD17B10 (0.46) | HTTL3MBTL1MAPTNPSR1KMT2A | |
| SCHEMBL11638099 | 0.74 | POLB (0.48) | HTTPKML3MBTL1MAPTNPSR1 | |
| SCHEMBL23579968 | 0.72 | MAPT (0.47) | HTTPKML3MBTL1MAPTNPSR1 | |
| SCHEMBL14366623 | 0.72 | MAPT (0.40) | HTTMAPTNPSR1KMT2AMEN1 | |
| SCHEMBL2231380 | 0.72 | ALDH1A1 (0.63) | HTTL3MBTL1MAPTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542869-A2 | MOLECULAR SCALE ELECTRONIC DEVICES | Yale University (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1542869-A4 | MOLECULAR SCALE ELECTRONIC DEVICES | UNIV YALE (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20050101063-A1 | Three-terminal field-controlled molecular devices | TOUR JAMES M (US) | 2005-05-12 | — | — | US | disclosed |
| US-6756605-B1 | Molecular scale electronic devices | YALE UNIVERSITY | 2004-06-29 | — | — | US | disclosed |
| WO-2001027972-A9 | MOLECULAR SCALE ELECTRONIC DEVICES | UNIV YALE (US) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002035580-A2 | THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES | MOLECULAR ELECTRONICS CORPORATION (US) | 2002-05-02 | — | — | WO | disclosed |
| WO-2001027972-A2 | MOLECULAR SCALE ELECTRONIC DEVICES | YALE UNIVERSITY (US) | 2001-04-19 | — | — | WO | disclosed |